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袁生

教授,博导/ Professor

1997年,北京师范大学生物系细胞生物学专业 博士

2001年,美国宾夕法尼亚州立大学生物学系?? 博士后

江苏省有突出贡献中青年专家、省六大人才高峰人选

1997, Ph.D., Cell Biology, the Department of Biology, Beijing Normal University??

2001, Postdoc., the Department of Biology, the Pennsylvania State University

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主要研究领域与方向/Main Research Fields

微生物生长调控的分子生物学研究:酵母细胞增殖、担子菌生长发育

微生物代谢调控与药物合成研究:微生物转化合成药物、农药及其中间体

Molecular mechanism of microbial growth regulation: Yeast cell cycle, growth and development of fruit bodies in basidiomycetes

■Microbial metabolism regulation and drugs synthesis: Microbial transformation for synthesis of medicines, pesticides and chemical intermediates

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主要在研项目/Selected Research Grants

金针菇菌柄细胞壁伸长作用的分子机制研究,国家自然科学基金面上项目,65, 2012-2015

■RPL32-2介导的基因转录调控及其在裂殖酵母营养生长细胞与沉默细胞相互转换中的作用,国家自然?????

科学基金面上项目,45, 2011-2013

食用菌工厂化高产栽培技术与菌糠综合利用技术研究, 南京市科技转化项目,50万, 2009-2012

科研训练及科研能力提高项目, 国家自然科学基金基础科学人才培养基金项目,400万,2012-2015

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近期代表性论文/Selected Publications:

■Wang J, S Yuan* an S-B Jiang (2006). The Ribosomal Protein L32-2 (RPL32-2) of S. Pombe Exhibits a Novel Extraribosomal Function by Acting As a Potential Transcriptional Regulator. FEBS Lett5801827-1832.

Zhao Q-X, S. Yuan*, X. Wang, Y-L. Zhang, H. Zhu, C-M. Lu (2008). Restoration of mature etiolated cucumber hypocotyl cell wall susceptibility to expansin by pretreatment with fungal pectinases and EGTA in vitro. Plant Physiol. 2008; 147(4):1874-1885.

■Wei W, C Yang, J Luo, C-M Lu, Y-J Wu, S Yuan* (2010). Synergism between cucumber-expansin, fungal endoglucanase and pectin lyase. J Plant Physiol, , 167, 1204–1210.

■Jiang J.-R., S. Yuan*, J.-F. Ding , S-C Zhu, H.-D. Xu, T. Chen, X.-D Cong, W.-P. Xu, H. Ye, Y-J Dai (2008) Conversion of puerarin into its 7-O-glycoside derivatives by Microbacterium oxydans (CGMCC 1788) to improve its water solubility and pharmacokinetic properties. Appl Microbiol Biotech, 81,647-657

■Yu C-G, H-D Xu, G-D Huang, T Chen, G-Y Liu, N Chai, Y-J Dai, S Yuan* (2010) Permeabilization of Microbacterium oxydans CGMCC 1788 with ethanol results in changes of transformation products composition of puerarin. Appl Microbiol Biotech, 86, 863–870.

■Yang Y, S Yuan*, T Chen, P-J Ma, G-D Shang, Y-J Dai.2009Cloning, heterologous expression, and functional characterization of the nicotinate dehydrogenase gene from Pseudomonas putida KT2440. Biodegradation. 20 (4):541-549.

*联系作者/Corresponding author

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联系方式/ Contact:

电话/Tel: 025-85891067?? 传真/Fax: 025-85861067?? E-mail: yuansheng@njnu.edu.cn

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